Surviving rapamycin

Rapamycin

Vaccines that generate Ag-specific CD8(+) T-cell responses of appropriate quality, magnitude and duration are highly desirable. The ability of mTOR to regulate CD8(+) T-cell functional differentiation must be exploited for clinical benefit. In a recent paper, we report that varying the regimen of rapamycin administration regulates viral vaccine-induced CD8(+) T-cell responses for tumor immunity...

Surviving torture.

Rapamycin.

Purpose of the Study Pulmonary metastasis continues to be the major cause of mortality among human and canine patients with osteosarcoma. A series of investigational agents will be evaluated in dogs with appendicular osteosarcoma with the hopes of identifying new drugs that help dogs live longer after being diagnosed with osteosarcoma. Rapamycin is a drug that may help slow down the progression...

Surviving Internet Catastrophes

In this paper, we propose a new approach for designing distributed systems to survive Internet catastrophes called informed replication, and demonstrate this approach with the design and evaluation of a cooperative backup system called the Phoenix Recovery Service. Informed replication uses a model of correlated failures to exploit software diversity. The key observation that makes our approach...

Surviving Global Software Development

0 7 4 0 7 4 5 9 / 0 1 / $ 1 0 . 0 0 © 2 0 0 1 I E E E Working in a global context has its advantages, but it also has drawbacks. On the plus side, you gain time-zone effectiveness and reduced cost in various countries. However, working on a globally distributed project means operating costs for planning and managing people, along with language and cultural barriers. It also creates jealousy as ...